PPP1R12B anticorps (Middle Region)

N° du produit ABIN5517282

Cet anticorps Lapin Polyclonal détecte spécifiquement PPP1R12B dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PPP1R12B anticorps (Middle Region) (ABIN5517282)

Antigène: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R12B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PPP1R12B anticorps

Épitope: Middle Region

Séquence: FNKPEEPKDE SPSSWRLGLR KTGSHNMLSE VANSREPIRD RGSSIYRSSS

Attributs du produit: This is a rabbit polyclonal antibody against MYPT2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen for Anti-PPP1R12B antibody is: synthetic peptide directed towards the Middle region of Human MYPT2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PPP1R12B

Antigène: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Autre désignation: PPP1R12B

Sujet: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.

Alias Symbols: MYPT2, PP1bp55

Protein Size: 982

ID gène: 4660

UniProt: O60237

Pathways: M Phase