UBXN1 anticorps (C-Term)

N° du produit ABIN5517552

Détail du produit anti-UBXN1 anticorps

Antigène: UBXN1 (UBX Domain Protein 1 (UBXN1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBXN1 est non-conjugé

Application: Western Blotting (WB)

Séquence: RAKKYGGSVG SQPPPVAPEP GPVPSSPSQE PPTKREYDQC RIQVRLPDGT

Attributs du produit: This is a rabbit polyclonal antibody against UBXN1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBXN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBXN1

Antigène: UBXN1 (UBX Domain Protein 1 (UBXN1))

Autre désignation: UBXN1 (UBXN1 Produits)

Synonymes: anticorps 2B28, anticorps SAKS1, anticorps UBXD10, anticorps 4930455J02Rik, anticorps D19Ertd721e, anticorps T25529, anticorps RGD1309471, anticorps fb49a05, anticorps wu:fb49a05, anticorps zgc:77531, anticorps UBX domain protein 1, anticorps UBXN1, anticorps Ubxn1, anticorps ubxn1

Sujet: UBXN1 is a ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. It specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, it leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. It is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

Alias Symbols: SAKS1

Protein Size: 297

ID gène: 51035

UniProt: Q04323