ZCCHC6 anticorps (N-Term)

N° du produit ABIN5517595

L’anticorps anti-ZCCHC6 Polyclonal Lapin est utilisé pour la détection de ZCCHC6 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ZCCHC6 anticorps (N-Term) (ABIN5517595)

Antigène: ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZCCHC6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZCCHC6 anticorps

Épitope: N-Term

Séquence: SPENKKQRSR PRKPRKTRNE ENEQDGDLEG PVIDESVLST KELLGLQQAE

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ZCCHC6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZCCHC6

Antigène: ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))

Autre désignation: ZCCHC6

Sujet: Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7 (pre-let-7). Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation. Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A. Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.

Alias Symbols: TUT7, PAPD6

Protein Size: 544

ID gène: 79670

NCBI Accession: NM_001185059, NP_001171988