PKDCC anticorps (N-Term)

N° du produit ABIN5517602

Cet anticorps anti-PKDCC Polyclonal Lapin (ABIN5517602) détecte spécifiquement PKDCC dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PKDCC anticorps (N-Term) (ABIN5517602)

Antigène: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKDCC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PKDCC anticorps

Épitope: N-Term

Fonction: PKDCC Antibody - N-terminal region

Séquence: GGRGELARQI RARYEEVQRY SRGGPGPGAG RPERRRLMDL APGGPGLPRP

Homologie: Cow: 100%, Dog: 78%, Human: 100%, Mouse: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PKDCC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62899-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PKDCC

Antigène: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Autre désignation: PKDCC

Sujet:

Background Information: Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane.

Gene Name: protein kinase domain containing, cytoplasmic

Alternative Symbols: Vlk, RLSDF, SGK493

Protein Name: Extracellular tyrosine-protein kinase PKDCC

Poids moléculaire: 54 kDa

ID gène: 91461

NCBI Accession: NP_612379

UniProt: Q504Y2