PYDC1 anticorps (N-Term)

N° du produit ABIN5517612

Détail du produit anti-PYDC1 anticorps

Antigène: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Épitope: N-Term

Reactivité: Humain, Saccharomyces cerevisiae, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYDC1 est non-conjugé

Application: Western Blotting (WB)

Séquence: REAILKVLEN LTPEELKKFK MKLGTVPLRE GFERIPRGAL GQLDIVDLTD

Homologie: Cow: 83%, Dog: 83%, Goat: 83%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against PYDC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PYDC1

Antigène: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Autre désignation: PYDC1 (PYDC1 Produits)

Synonymes: anticorps ASC2, anticorps POP1, anticorps PYC1, anticorps pyrin domain containing 1, anticorps PYDC1

Sujet: PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

Alias Symbols: PYDC1, ASC2, ASCI, POP1, PYC1,

Protein Interaction Partner: WDR82,

Protein Size: 89

ID gène: 260434

NCBI Accession: NP_690865

UniProt: Q8WXC3