PYDC1 anticorps (N-Term)
Aperçu rapide pour PYDC1 anticorps (N-Term) (ABIN5517612)
Antigène
Voir toutes PYDC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- PYDC1 Antibody - N-terminal region
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Séquence
- REAILKVLEN LTPEELKKFK MKLGTVPLRE GFERIPRGAL GQLDIVDLTD
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Homologie
- Cow: 83%, Dog: 83%, Goat: 83%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Yeast: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against PYDC1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55560-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
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Autre désignation
- PYDC1
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Sujet
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Background Information: PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
Gene Name: PYD (pyrin domain) containing 1
Alternative Symbols: ASC2, POP1, PYC1, cPOP1
Protein Name: Pyrin domain-containing protein 1
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Poids moléculaire
- 9kDa
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ID gène
- 260434
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NCBI Accession
- NP_690865
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UniProt
- Q8WXC3
Antigène
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