STIL anticorps (N-Term)

N° du produit ABIN5517883

Détail du produit anti-STIL anticorps

Antigène: STIL (SCL/TAL1 Interrupting Locus (STIL))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STIL est non-conjugé

Application: Western Blotting (WB)

Séquence: QKLSSGKMPI HDHDSGVEDE DFSPRPIPSP HPVSQKISKI QPSVPELSLV

Attributs du produit: This is a rabbit polyclonal antibody against STIL. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human STIL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STIL

Antigène: STIL (SCL/TAL1 Interrupting Locus (STIL))

Autre désignation: STIL (STIL Produits)

Synonymes: anticorps Sil, anticorps MCPH7, anticorps SIL, anticorps chunp6907, anticorps sill, anticorps zgc:110502, anticorps STIL, centriolar assembly protein, anticorps Scl/Tal1 interrupting locus, anticorps STIL, centriolar assembly protein L homeolog, anticorps scl/tal1 interrupting locus, anticorps Stil, anticorps STIL, anticorps stil.L, anticorps stil

Sujet: This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: SIL

Protein Size: 1287

ID gène: 6491

UniProt: Q15468

Pathways: Tube Formation