COQ3 anticorps (Middle Region)

N° du produit ABIN5517895

L’anticorps anti-COQ3 Polyclonal Lapin est utilisé pour la détection de COQ3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour COQ3 anticorps (Middle Region) (ABIN5517895)

Antigène: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COQ3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COQ3 anticorps

Épitope: Middle Region

Fonction: COQ3 Antibody - middle region

Séquence: CGGGLLTEPL GRLGASVIGI DPVDENIKTA QCHKSFDPVL DKRIEYRVCS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against COQ3. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human COQ3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48797-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur COQ3

Antigène: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Autre désignation: COQ3

Sujet:

Background Information: Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.

Gene Name: coenzyme Q3 homolog, methyltransferase (S. cerevisiae)

Alternative Symbols: DHHBMT, bA9819.1, DHHBMTASE, UG0215E05

Protein Name: Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial

Poids moléculaire: 40kDa

ID gène: 51805

NCBI Accession: NP_059117

UniProt: Q9NZJ6

Pathways: Methionine Biosynthetic Process