ALPL anticorps (N-Term)

N° du produit ABIN5518639

Détail du produit anti-ALPL anticorps

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Épitope: AA 18-32, N-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALPL est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Alkaline phosphatase, tissue-nonspecific isozyme(ALPL) detection. Tested with WB, IHC-P in Mouse,Rat.

Séquence: FVPEKEKDPS YWRQQ

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Alkaline phosphatase, tissue-nonspecific isozyme(ALPL) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: alkaline phosphatase, liver/bone/kidney
Protein Name: Alkaline phosphatase, tissue-nonspecific isozyme

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of rat Alkaline Phosphatase(18-32aa, FVPEKEKDPSYWRQQ), different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-ALPL (ABIN5518639)

Sun, Jiang, Chen, Xue, Mao, Ruan, Song, Mustea: "Decreasing the ratio of matriptase/HAI‑1 by downregulation of matriptase as a potential adjuvant therapy in ovarian cancer." dans: Molecular medicine reports, Vol. 14, Issue 2, pp. 1465-74, (2017) (PubMed).

Hou, Huang, Luo, Wang, Liu, Deng, Zhang, Liu, Chen: "MiR-351 negatively regulates osteoblast differentiation of MSCs induced by (+)-cholesten-3-one through targeting VDR." dans: American journal of translational research, Vol. 9, Issue 11, pp. 4963-4973, (2017) (PubMed).

Liu, Deng, Zhang, Zhang: "Wnt3a expression during the differentiation of adipose-derived stem cells into cholinergic neurons." dans: Neural regeneration research, Vol. 7, Issue 19, pp. 1463-8, (2015) (PubMed).

Xu, Dong, Huang, Li, Qin, Ren, Guo, Chen, Huang: "Decreased osteoclastogenesis, osteoblastogenesis and low bone mass in a mouse model of type 2 diabetes." dans: Molecular medicine reports, Vol. 10, Issue 4, pp. 1935-41, (2014) (PubMed).

Liu, Lu, Wu, Yan: "A multi-biomarker assessment of single and combined effects of norfloxacin and sulfamethoxazole on male goldfish (Carassius auratus)." dans: Ecotoxicology and environmental safety, Vol. 102, pp. 12-7, (2014) (PubMed).

Guo, Shi, Liu, Lin, Bi, Shi, Yan: "Cartilage oligomeric matrix protein gene multilayers inhibit osteogenic differentiation and promote chondrogenic differentiation of mesenchymal stem cells." dans: International journal of molecular sciences, Vol. 15, Issue 11, pp. 20117-33, (2014) (PubMed).

Feng, Zhu, Zhang, Jia, Cheng, Ding, Zhu et al.: "Amelioration of compound 4,4'-diphenylmethane-bis(methyl)carbamate on high mobility group box1-mediated inflammation and oxidant stress responses in human umbilical vein endothelial cells via ..." dans: International immunopharmacology, Vol. 15, Issue 2, pp. 206-16, (2013) (PubMed).

Shen, Zhan, Deng, Ren, Ye, Xiao, Guo: "MicroRNA-519a demonstrates significant tumour suppressive activity in laryngeal squamous cells by targeting anti-carcinoma HuR gene." dans: The Journal of laryngology and otology, Vol. 127, Issue 12, pp. 1194-202, (2013) (PubMed).

Zhang, Wu, Hu, Wang, Li: "Rho kinase inhibitor Y-27632 and Accutase dramatically increase mouse embryonic stem cell derivation." dans: In vitro cellular & developmental biology. Animal, Vol. 48, Issue 1, pp. 30-6, (2012) (PubMed).

Zhang, Yang, Jiang, Fang, Xiong, Cheng, Xia: "The lupus-derived anti-double-stranded DNA IgG contributes to myofibroblast-like phenotype in mesangial cells." dans: Journal of clinical immunology, Vol. 32, Issue 6, pp. 1270-8, (2012) (PubMed).

Li, Xia, Tang, Wang, Bei, Zeng: "In vitro and in vivo biocompatibility investigation of diamond-like carbon coated nickel-titanium shape memory alloy." dans: Artificial cells, blood substitutes, and immobilization biotechnology, Vol. 39, Issue 3, pp. 137-42, (2011) (PubMed).

Su, Wang, Qi, Zhao, Li, Cui: "Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell proliferation of pterygium fibroblasts." dans: Molecular vision, Vol. 17, pp. 247-56, (2011) (PubMed).

Zhao, Gao, Mei, Li, Wang: "Differentiation of human mesenchymal stem cells: the potential mechanism for estrogen-induced preferential osteoblast versus adipocyte differentiation." dans: The American journal of the medical sciences, Vol. 341, Issue 6, pp. 460-8, (2011) (PubMed).

Wang, Huang, Feng, Chen, Tang, Chen: "Expression, purification, and characterization of functional recombinant human daintain/AIF-1 in Escherichia coli." dans: Zeitschrift fu?r Naturforschung. C, Journal of biosciences, Vol. 65, Issue 11-12, pp. 726-32, (2011) (PubMed).

Lai, Yan, Wu, Leng, Ju: "Ultrasensitive multiplexed immunoassay with electrochemical stripping analysis of silver nanoparticles catalytically deposited by gold nanoparticles and enzymatic reaction." dans: Analytical chemistry, Vol. 83, Issue 7, pp. 2726-32, (2011) (PubMed).

Shen, Ren, Ye, Guo, Kang, Ding: "Significance and relationship between DJ-1 gene and surviving gene expression in laryngeal carcinoma." dans: European journal of histochemistry : EJH, Vol. 55, Issue 1, pp. e9, (2011) (PubMed).

Guan, Wang, Hou, Chen, Li, Yue, Ma: "Derivation and characteristics of pluripotent embryonic germ cells in duck." dans: Poultry science, Vol. 89, Issue 2, pp. 312-7, (2010) (PubMed).

Song, Lu, Wang, Zhang, Xu, Qin: "Study on environmental estrogen pollution in Yangtze River (Nanjing section) by an in vivo bioassay." dans: Bulletin of environmental contamination and toxicology, Vol. 84, Issue 4, pp. 406-12, (2010) (PubMed).

Lu, Song, Wang, Yan: "Assessment of in vivo estrogenic response and the identification of environmental estrogens in the Yangtze River (Nanjing section)." dans: Chemosphere, Vol. 80, Issue 9, pp. 982-90, (2010) (PubMed).

Li, Yan, Han, Zhang: "Mimotope vaccination for epitope-specific induction of anti-CD20 antibodies." dans: Cellular immunology, Vol. 239, Issue 2, pp. 136-43, (2006) (PubMed).

Détails sur ALPL

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Autre désignation: ALPL (ALPL Produits)

Synonymes: anticorps ALP, anticorps iap, anticorps alpl, anticorps AP-TNAP, anticorps APTNAP, anticorps HOPS, anticorps TNAP, anticorps TNSALP, anticorps Akp-2, anticorps Akp2, anticorps PHOA, anticorps TNS-AP, anticorps alkaline phosphatase, liver/bone/kidney L homeolog, anticorps alkaline phosphatase, liver/bone/kidney, anticorps alkaline phosphatase, intestinal, gene 2, anticorps alkaline phosphatase, liver/bone/kidney pseudogene, anticorps alpl.L, anticorps ALPL, anticorps alpi.2, anticorps LOC100031702, anticorps Alpl

Sujet: Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. Liver/bone/kidney alkaline phosphatase, also known as tissue-nonspecific alkaline phosphatase, acts physiologically as a lipid-anchored phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP) ectophosphatase Mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.

Synonyms: Akp2 antibody|Alkaline phosphatase intestinal antibody|Alkaline phosphatase intestinal precursor antibody|Alkaline phosphatase liver/bone/kidney antibody|Alkaline phosphatase placental antibody|Alkaline phosphatase placental like 2 antibody|Alkaline phosphatase placental like antibody|Alkaline phosphatase placental type antibody|Alkaline phosphomonoesterase antibody|ALP 1 antibody|ALP antibody|ALP I antibody|ALP L antibody|ALP P antibody|ALPG antibody|ALPI antibody|ALPL antibody|ALPP antibody|ALPPL antibody|ALPPL2 antibody|AP TNAP antibody|FLJ40094 antibody|GCAP antibody|Germ cell alkaline phosphatase antibody|Glycerophosphatase antibody|HOPS antibody|IAP antibody|Intestinal alkaline phosphatase antibody|Kasahara isozyme antibody|Nagao isozyme antibody|OTTHUMP00000164357 antibody|Placental alkaline phosphatase antibody|Placental like alkaline phosphatase antibody|PLAP 1 antibody|PLAP antibody|PLAP like antibody|Regan isozyme antibody|Testicular and thymus alkaline phosphatase antibody|Tissue non specific alkaline phosphatase antibody|Tissue nonspecific ALP antibody|TNAP antibody|TNSALP antibody

UniProt: P08289