LASP1 anticorps (C-Term)

N° du produit ABIN5518689

Cet anticorps Lapin Polyclonal détecte spécifiquement LASP1 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour LASP1 anticorps (C-Term) (ABIN5518689)

Antigène: LASP1 (LIM and SH3 Protein 1 (LASP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LASP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-LASP1 anticorps

Épitope: AA 152-168, C-Term

Fonction: Anti-LIM and SH3 domain protein 1 LASP1 Antibody Picoband®

Séquence: YRRPLEQQQP HHIPTSA

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-LIM and SH3 domain protein 1 LASP1 Antibody (ABIN5518689). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human LASP1.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Schreiber, V., Masson, R., Linares, J. L., Mattei, M. G., Tomasetto, C., Rio, M. C.Chromosomal assignment and expression pattern of the murine Lasp-1 gene.Gene 207: 171-175, 1998. 2. Tomasetto, C., Moog-Lutz, C., Regnier, C. H., Schreiber, V., Basset, P., Rio, M.-C.Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains.FEBS Lett. 373: 245-249, 1995. 3. Tomasetto, C., Regnier, C., Moog-Lutz, C., Mattei, M. G., Chenard, M. P., Lidereau, R., Basset, P., Rio, M. C.Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.Genomics 28: 367-376, 1995.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) .

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur LASP1

Antigène: LASP1 (LIM and SH3 Protein 1 (LASP1))

Autre désignation: LASP1

Sujet:

Synonyms: LIM and SH3 domain protein 1,LASP-1,Metastatic lymph node gene 50 protein,MLN 50,LASP1,MLN50,

Background: LASP1 (LIM and SH3 domain protein 1), also known as LASP1, is a protein that in humans is encoded by the LASP1 gene. This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. LASP1 has been shown to interact with Zyxin. Tomasetto et al. (1995) mapped the LASP1 gene to chromosome 17q11-q21.3 by radioactive in situ hybridization. Northern blot analysis revealed that LASP1 mRNA was expressed at a basal level in all normal tissues examined and overexpressed in 8 % of primary breast cancers. In most of these cancers, LASP1 and ERBB2 were simultaneously overexpressed.

Sequence Similarities: Contains 1 LIM zinc-binding domain.

Poids moléculaire: 11 kDa

UniProt: Q14847