CYGB anticorps (AA 1-190)

N° du produit ABIN5518753

L’anticorps Lapin Polyclonal anti-CYGB a été validé pour WB et IHC. Il convient pour détecter CYGB dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour CYGB anticorps (AA 1-190) (ABIN5518753)

Antigène: CYGB (Cytoglobin (CYGB))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYGB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CYGB anticorps

Épitope: AA 1-190

Fonction: Anti-Cytoglobin/CYGB Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Cytoglobin/CYGB Antibody Picoband® (ABIN5518753). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cytoglobin recombinant protein (Position: M1-P190). Human Cytoglobin shares 95.3% and 93.7% amino acid (aa) sequence identity with mouse and rat Cytoglobin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. Asahina, K., Kawada, N., Kristensen, D. B., Nakatani, K., Seki, S., Shiokawa, M., Tateno, C., Obara, M., Yoshizato, K. Characterization of human stellate cell activation-associated protein and its expression in human liver. Biochim. Biophys. Acta 1577: 471-475, 2002. 2. Burmester, T., Ebner, B., Weich, B., Hankeln, T. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Molec. Biol. Evol. 19: 416-421, 2002. 3. Geuens, E., Brouns, I., Flamez, D., Dewilde, S., Timmermans, J.-P., Moens, L. A globin in the nucleus! J. Biol. Chem. 278: 30417-30420, 2003.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CYGB

Antigène: CYGB (Cytoglobin (CYGB))

Autre désignation: CYGB

Sujet:

Synonyms: Cytoglobin,Histoglobin,HGb,Stellate cell activation-associated protein,CYGB,STAP,

Tissue Specificity: Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. .

Background: Cytoglobin (CYGB), also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The cytoglobin gene is mapped on 17q25.1. The CYGB gene contains 4 exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir.

Poids moléculaire: 21 kDa

ID gène: 114757