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HBV Large S Protein anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement HBV Large S Protein dans WB et IHC. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.
N° du produit ABIN5518758

Aperçu rapide pour HBV Large S Protein anticorps (N-Term) (ABIN5518758)

Antigène

HBV Large S Protein (L-HBsAG) (Hepatitis B Virus Large Surface Protein (L-HBsAG))

Reactivité

Humain

Hôte

  • 16
Lapin

Clonalité

  • 16
Polyclonal

Conjugué

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HBV Large S Protein est non-conjugé

Application

  • 16
  • 13
  • 13
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    AA 4-51, N-Term

    Fonction

    Anti-Hepatitis B Virus Antibody Picoband®

    Séquence

    WSSKPRQGMG TNLSVPNPLG FFPDHQLDPA FGANSNNPDW DFNPNKDQ

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Rabbit IgG polyclonal antibody for Large S protein(S) detection. Tested with WB, IHC-P in Human,HBV.
    Gene Name: long surface protein, PreS1, L protein, LHBs, large S protein, pre-S1/pre-S2/S regions, L glycoprotein, L-HBsAG, LHBs
    Protein Name: Large S protein

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human Hepatitis B Virus.

    Isotype

    IgG
  • Indications d'application

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, HBV
    1. Magnius LO, Norder H (1995). "Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene". Intervirology. 38 (1-2): 24-34. 2. Rysgaard, Carolyn D, Morris, Cory S, Drees, Denny, Bebber, Tami, Davis, Scott R, Kulhavy, Jeff, Krasowski, Matthew D (2012). "Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem". BMC Clinical Pathology. 12 (1): 15. doi:10.1186/1472-6890-12-15. Retrieved11 March 2014.

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Xiangji, Feng, Qingbao, Weifeng, Xiaoqing, Baihe, Feng, Hongyang, Mengchao: "Knockdown of HBV surface antigen gene expression by a lentiviral microRNA-based system inhibits HBV replication and HCC growth." dans: Journal of viral hepatitis, Vol. 18, Issue 9, pp. 653-60, (2011) (PubMed).

    Zhang, Wang, Li, Qiao: "Expression of transforming growth factor-alpha and hepatitis B surface antigen in human hepatocellular carcinoma tissues and its significance." dans: World journal of gastroenterology, Vol. 10, Issue 6, pp. 830-3, (2004) (PubMed).

    Paliaga, Braga: "Passive limitation of adduction after Cüppers's 'Fadenoperation' on medial recti." dans: The British journal of ophthalmology, Vol. 73, Issue 8, pp. 633-5, (1989) (PubMed).

    Ramsey: "Should medicine today be taught without medical ethics?" dans: Connecticut medicine, Vol. 37, Issue 8, pp. 420-1, (1973) (PubMed).

  • Antigène

    HBV Large S Protein (L-HBsAG) (Hepatitis B Virus Large Surface Protein (L-HBsAG))

    Autre désignation

    S

    Classe de substances

    Viral Protein

    Sujet

    Synonyms: Large S protein ,S ,

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: Hepatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B. It consists of HBsAg, HBcAg (HBeAg is a splice variant), Hepatitis B virus DNA polymerase and HBx. Among these, HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). It indicates current hepatitis B infection. The viral envelope of an enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.

    Poids moléculaire

    6 kDa

    UniProt

    D2X4M3
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