LMO1 anticorps (C-Term)

N° du produit ABIN5518772

Cet anticorps anti-LMO1 est un anticorps Lapin Polyclonal détectant LMO1 dans WB. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour LMO1 anticorps (C-Term) (ABIN5518772)

Antigène: LMO1 (LIM Domain Only 1 (Rhombotin 1) (LMO1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMO1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LMO1 anticorps

Épitope: AA 127-156, C-Term

Fonction: Anti-LMO1 Antibody Picoband®

Séquence: DKFFLKNNMI LCQMDYEEGQ LNGTFESQVQ

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-LMO1 Antibody Picoband® (ABIN5518772). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human LMO1, different from the related mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)". 2. Boehm T, Foroni L, Kaneko Y, Perutz MF, Rabbitts TH (June 1991). "The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13". Proc Natl Acad Sci U S A. 88 (10): 4367-71. 3. McGuire EA, Davis AR, Korsmeyer SJ (March 1991). "T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells". Blood. 77 (3): 599-606.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur LMO1

Antigène: LMO1 (LIM Domain Only 1 (Rhombotin 1) (LMO1))

Autre désignation: LMO1

Sujet:

Synonyms: Rhombotin-1,Cysteine-rich protein TTG-1,LIM domain only protein 1,LMO-1,T-cell translocation protein 1,LMO1,RBTN1, RHOM1, TTG1,

Tissue Specificity: Expressed mainly in the central nervous. Low level of expression in other tissues including thymus. .

Background: Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene. This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions, thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

Poids moléculaire: 18 kDa

ID gène: 4004

UniProt: P25800

Pathways: Dopaminergic Neurogenesis