ALDH1A3 anticorps (AA 37-154)
Aperçu rapide pour ALDH1A3 anticorps (AA 37-154) (ABIN5518802)
Antigène
Voir toutes ALDH1A3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 37-154
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Fonction
- Anti-ALDH1A3 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-ALDH1A3 Antibody (ABIN5518802). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human ALDH1A3 recombinant protein (Position: N37-K154). Human ALDH1A3 shares 89% and 87.3% amino acid (aa) sequence identity with mouse and rat ALDH1A3, respectively.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
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Autre désignation
- ALDH1A3
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Sujet
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Synonyms: Aldehyde dehydrogenase family 1 member A3,1.2.1.5,Aldehyde dehydrogenase 6,Retinaldehyde dehydrogenase 3,RALDH-3,RalDH3,ALDH1A3,ALDH6,
Tissue Specificity: Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Background: Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene. Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 50-56 kDa
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ID gène
- 220
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UniProt
- P47895
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Pathways
- Retinoic Acid Receptor Signaling Pathway
Antigène
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