GJC1 anticorps (N-Term)

N° du produit ABIN5518838

Cité dans 1 publication. Cet anticorps anti-GJC1 Polyclonal Lapin (ABIN5518838) détecte spécifiquement GJC1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour GJC1 anticorps (N-Term) (ABIN5518838)

Antigène: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GJC1 anticorps

Épitope: N-Term

Fonction: Anti-Connexin 45/GJA7/GJC1 Antibody

Séquence: YLGYAIHKIA KMEHGEADKK AARSKPYAMR WKQHRALEET E

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Attributs du produit: Anti-Connexin 45/GJA7/GJC1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Connexin 45/GJA7, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat Western blot, 0.1-0.5 μg/mL, Rat, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-GJC1 (ABIN5518838)

Zeng, Li, Li, Li, Xiao, Chu, Yang: "Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins expression in diabetic rats." dans: Bioengineered, Vol. 7, Issue 5, pp. 314-320, (2017) (PubMed).

Détails sur GJC1

Antigène: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Autre désignation: GJC1

Sujet:

Background: Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) or connexin 45 (Cx45), is a protein that in humans is encoded by the GJC1 gene. The International Radiation Hybrid Mapping Consortium mapped the GJA7 gene to chromosome 17q21.31. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell.

Gene Full Name: gap junction protein gamma 1

Poids moléculaire: 45 kDa

ID gène: 10052

UniProt: P36383

Pathways: Cell-Cell Junction Organization