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IFNGR1 anticorps (N-Term)

Cet anticorps anti-IFNGR1 est un anticorps Lapin Polyclonal détectant IFNGR1 dans WB et FACS. Adapté pour Humain.
N° du produit ABIN5518850

Aperçu rapide pour IFNGR1 anticorps (N-Term) (ABIN5518850)

Antigène

Voir toutes IFNGR1 Anticorps
IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivité

  • 57
  • 34
  • 8
  • 6
Humain

Hôte

  • 51
  • 12
  • 9
  • 6
  • 3
  • 2
Lapin

Clonalité

  • 55
  • 27
  • 1
Polyclonal

Conjugué

  • 50
  • 11
  • 7
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp IFNGR1 est non-conjugé

Application

  • 49
  • 31
  • 25
  • 22
  • 14
  • 12
  • 9
  • 8
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • Épitope

    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 108-147, N-Term

    Fonction

    Anti-IFNGR1 Antibody Picoband®

    Séquence

    QKESAYAKSE EFAVCRDGKI GPPKLDIRKE EKQIMIDIFH

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-IFNGR1 Antibody Picoband® (ABIN5518850). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human IFNGR1, different from the related mouse sequence by eighteen amino acids.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: IFNGR1 interferon gamma receptor 1". 2. Aguet M, Dembi99 Z, Merlin G (Oct 1988). "Molecular cloning and expression of the human interferon-gamma receptor". Cell. 55 (2): 273-80. 3. Novick D, Orchansky P, Revel M, Rubinstein M (Jun 1987). "The human interferon-gamma receptor. Purification, characterization, and preparation of antibodies". The Journal of Biological Chemistry. 262(18): 8483-7.

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

    Autre désignation

    IFNGR1

    Sujet

    Synonyms: Interferon gamma receptor 1,IFN-gamma receptor 1,IFN-gamma-R1,CDw119,CD119,IFNGR1,

    Tissue Specificity: Liver and small intestine. Also found in ovary, testis and kidney.

    Background: Interferon gamma receptor 1 (IFNGR1), also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene. This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

    Poids moléculaire

    95 kDa

    ID gène

    3459

    UniProt

    P15260

    Pathways

    Interferon-gamma Pathway
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