KRT8 anticorps (AA 107-325)

N° du produit ABIN5518853

Détail du produit anti-KRT8 anticorps

Antigène: KRT8 (Keratin 8 (KRT8))

Épitope: AA 107-325

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KRT8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Keratin, type II cytoskeletal 8(KRT8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Keratin, type II cytoskeletal 8(KRT8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: keratin 8
Protein Name: Keratin, type II cytoskeletal 8

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cytokeratin 8 recombinant protein (Position: D107-K325). Human Cytokeratin 8 shares 95.4% and 94.5% amino acid (aa) sequence identity with mouse and rat Cytokeratin 8, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur KRT8

Antigène: KRT8 (Keratin 8 (KRT8))

Autre désignation: KRT8 (KRT8 Produits)

Synonymes: anticorps CARD2, anticorps CK-8, anticorps CK8, anticorps CYK8, anticorps K2C8, anticorps K8, anticorps KO, anticorps AA960620, anticorps AL022697, anticorps AU019895, anticorps Card2, anticorps EndoA, anticorps Krt-2.8, anticorps Krt2-8, anticorps CYKER, anticorps KRT2-8, anticorps KERATIN8, anticorps ck8, anticorps cyk8, anticorps k2c8, anticorps card2, anticorps krt2-5, anticorps MGC69490, anticorps KRT8, anticorps DreK8, anticorps cb186, anticorps krt2-8, anticorps sb:cb186, anticorps wu:fa20h05, anticorps wu:fa95h10, anticorps wu:fb96c06, anticorps zf-K8, anticorps zfk8, anticorps DKFZp468F2127, anticorps keratin 8, anticorps keratin 8 S homeolog, anticorps KRT8, anticorps Krt8, anticorps krt8.S, anticorps krt8

Sujet: Keratin, type II cytoskeletal 8, also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Synonyms: Keratin, type II cytoskeletal 8 | Cytokeratin-8 | CK-8 | Keratin-8 | K8 | Type-II keratin Kb8 | KRT8 | CYK8 | P05787

ID gène: 3856

UniProt: P05787