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Myoglobin anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-Myoglobin a été validé pour WB et IHC. Il convient pour détecter Myoglobin dans des échantillons de Humain, Rat et Souris.
N° du produit ABIN5518936

Aperçu rapide pour Myoglobin anticorps (N-Term) (ABIN5518936)

Antigène

Voir toutes Myoglobin (MB) Anticorps
Myoglobin (MB)

Reactivité

  • 141
  • 95
  • 82
  • 17
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 102
  • 85
  • 8
  • 2
  • 1
  • 1
Lapin

Clonalité

  • 108
  • 89
Polyclonal

Conjugué

  • 94
  • 22
  • 15
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Myoglobin est non-conjugé

Application

  • 110
  • 79
  • 47
  • 39
  • 39
  • 30
  • 24
  • 20
  • 14
  • 13
  • 11
  • 10
  • 8
  • 8
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 33
    • 27
    • 15
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-35, N-Term

    Fonction

    Anti-Myoglobin/MB Antibody Picoband®

    Séquence

    LSDGEWQLVL NVWGKVEADI PGHGQEVLIR LFK

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Rabbit IgG polyclonal antibody for Myoglobin(MB) detection. Tested with WB in Human.
    Gene Name: myoglobin
    Protein Name: Myoglobin

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human Myoglobin, different from the related mouse sequence by three amino acids, and from the related rat sequence by six amino acids.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    1. Boyer, S. H., Fainer, D. C., Naughton, M. A. Myoglobin inherited structural variation in man. Science 140: 1228-1231, 1963. 2. Boulton, F. E., Huntsman, R. G., Lorkin, P. A., Lehmann, H. Abnormal human myoglobin: 53(D4) glutamic acid lysine. Nature 223: 832-833, 1969. 3. Jeffreys, A. J., Wilson, V., Blanchetot, A., Weller, P., Geurts van Kessel, A., Spurr, N., Solomon, E., Goodfellow, P. The human myoglobin gene: a third dispersed globin locus in the human genome. Nucleic Acids Res. 12: 3235-3243, 1984.

    Commentaires

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    Myoglobin (MB)

    Autre désignation

    Myoglobin

    Sujet

    Synonyms: Myoglobin,MB,

    Tissue Specificity: Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary.

    Background: Myoglobin (MB) also known as PVALB, is a single-chain globular protein of 153 or 154 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. It is a member of the globin superfamily and is expressed in skeletal and cardiac muscles. This gene is mapped to chromosome 22q11-q13. Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The released myoglobin is filtered by the kidneys but is toxic to the renal tubular epithelium and so may cause acute renal failure.

    Poids moléculaire

    17 kDa

    ID gène

    4151

    UniProt

    P02144

    Pathways

    Brown Fat Cell Differentiation
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