SIX Homeobox 6 anticorps (AA 188-246)

N° du produit ABIN5518956

Cet anticorps Lapin Polyclonal détecte spécifiquement SIX Homeobox 6 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour SIX Homeobox 6 anticorps (AA 188-246) (ABIN5518956)

Antigène: SIX Homeobox 6 (SIX6)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIX Homeobox 6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIX Homeobox 6 anticorps

Épitope: AA 188-246

Fonction: Anti-Homeobox protein SIX6 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Homeobox protein SIX6 Antibody Picoband® (ABIN5518956). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human SIX6 recombinant protein (Position: A188-I246). Human SIX6 shares 91.5% amino acid (aa) sequence identity with mouse SIX6.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
1. Aijaz, S., Clark, B. J., Williamson, K., van Heyningen, V., Morrison, D., FitzPatrick, D., Collin, R., Ragge, N., Christoforou, A., Brown, A., Hanson, I. Absence of SIX6 mutations in microphthalmia, anophthalmia, and coloboma. Invest. Ophthal. Vis. Sci. 45: 3871-3876, 2004. 2. Aldahmesh, M. A., Khan, A. O., Hijazi, H., Alkuraya, F. S. Homozygous truncation of SIX6causes complex microphthalmia in humans. (Letter) Clin. Genet. 84: 198-199, 2013. 3. Gallardo, M. E., Rodriguez de Cordoba, S., Schneider, A. S., Dwyer, M. A., Ayuso, C., Bovolenta, P. Analysis of the developmental SIX6 homeobox gene in patients with anophthalmia/microphthalmia. (Letter) Am. J. Med. Genet. 129A: 92-94, 2004.

Commentaires:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur SIX Homeobox 6

Antigène: SIX Homeobox 6 (SIX6)

Autre désignation: SIX6

Sujet:

Synonyms: Homeobox protein SIX6,Homeodomain protein OPTX2,Optic homeobox 2,Sine oculis homeobox homolog 6,SIX6,OPTX2, SIX9,

Tissue Specificity: Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.

Background: The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).

Poids moléculaire: 28 kDa

ID gène: 4990

UniProt: O95475