GSTP1 anticorps (AA 2-210)

N° du produit ABIN5518996

L’anticorps Lapin Polyclonal anti-GSTP1 a été validé pour WB, IHC et ELISA. Il convient pour détecter GSTP1 dans des échantillons de Humain, Souris et Rat. Il y a 3+ publications disponibles.

Aperçu rapide pour GSTP1 anticorps (AA 2-210) (ABIN5518996)

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-GSTP1 anticorps

Épitope: AA 2-210

Fonction: Anti-GST3/GST pi/Gstp1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-GST3/GST pi/Gstp1 Antibody Picoband® (ABIN5518996). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse GST3 / GST pi recombinant protein (Position: P2-Q210).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Bora PS, Bora NS, Wu XL, Lange LG (Oct 1991). "Molecular cloning, sequencing, and expression of human myocardial fatty acid ethyl ester synthase-III cDNA". J Biol Chem 266 (25): 16774-7. 2. Morrow, C. S., Cowan, K. H., Goldsmith, M. E. : Structure of the human genomic glutathione S-transferase-pi gene. Gene 75: 3-11, 1989. 3. Smith CM, Bora PS, Bora NS, Jones C, Gerhard DS (Nov 1995). "Genetic and radiation-reduced somatic cell hybrid sublocalization of the human GSTP1 gene". Cytogenet Cell Genet 71 (3): 235-9.

Commentaires:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-GSTP1 (ABIN5518996)

Zhang, Yan, Xu, Fang, Zhang, Zhang, Wu, Kong, Huang: "The recovery trajectory of adolescent social defeat stress-induced behavioral, (1)H-MRS metabolites and myelin changes in Balb/c mice." dans: Scientific reports, Vol. 6, pp. 27906, (2018) (PubMed).

Sun, Hu, Xiong, Tu, Zhao, Chen, Song, Ye: "Enhanced expression of stem cell markers and drug resistance in sphere-forming non-small cell lung cancer cells." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6287-300, (2016) (PubMed).

Yang, Gao, Zhang, Fang, Wu, Xu, Huang: "Changes in proinflammatory cytokines and white matter in chronically stressed rats." dans: Neuropsychiatric disease and treatment, Vol. 11, pp. 597-607, (2015) (PubMed).

Détails sur GSTP1

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Autre désignation: Gstp1

Sujet:

Synonyms: Glutathione S-transferase P 1, Gst P1, 2.5.1.18, GST YF-YF, GST class-pi, GST-piB, Preadipocyte growth factor, Gstp1, Gstpib,

Tissue Specificity: Ubiquitously expressed.

Background: Glutathione S-transferases pi (GSTP1), also known as GST3, is an enzyme that in humans is encoded by the GSTP1 gene. This gene is mapped to 11q13.2. GSTP1 has 7 exons and 6 introns contained within approximately 2.8 kilobases. GSTP1 belongs to Glutathione S-transferases (GSTs) which are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 presents in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. What's more, GSTP1 is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Poids moléculaire: 23 kDa

ID gène: 14870

UniProt: P19157

Pathways: Cellular Response to Molecule of Bacterial Origin