PVRL1 anticorps (PE)

N° du produit ABIN5526902

Détail du produit anti-PVRL1 anticorps (PE)

Antigène: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PVRL1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1), a 75 kDa type I transmembrane glycoprotein broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: NIH/3T3 cells transfected with human CD111

Clone: R1-302

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Commentaires:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur PVRL1

Antigène: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Autre désignation: CD111 (PVRL1 Produits)

Synonymes: anticorps CD111, anticorps CLPED1, anticorps ED4, anticorps HIgR, anticorps HVEC, anticorps OFC7, anticorps PRR, anticorps PRR1, anticorps PVRR, anticorps PVRR1, anticorps SK-12, anticorps nectin-1, anticorps prr1, anticorps PVRL1, anticorps pvrl1, anticorps AI835281, anticorps AW549174, anticorps Cd111, anticorps HveC, anticorps cd111, anticorps cd112, anticorps clped1, anticorps ed4, anticorps higr, anticorps hveb, anticorps hvec, anticorps nectin-2, anticorps ofc7, anticorps prr, anticorps prr2, anticorps pvrl2, anticorps pvrl2.L, anticorps pvrr, anticorps pvrr1, anticorps pvrr2, anticorps sk-12, anticorps nectin cell adhesion molecule 1, anticorps nectin-1, anticorps Poliovirus receptor-related protein 1, anticorps poliovirus receptor-related 1 (herpesvirus entry mediator C), anticorps nectin cell adhesion molecule 2 L homeolog, anticorps NECTIN1, anticorps LOC100145553, anticorps pvrl1, anticorps nectin1, anticorps Nectin1, anticorps PVRL1, anticorps nectin2.L

Sujet: Nectin cell adhesion molecule 1,CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.,NECTIN1, ED4, HIgR, HV1S, HVEC, OFC7, PRR1, PVRR, CD111, PVRL1, PVRR1, SK-12, CLPED1

ID gène: 5818

UniProt: Q15223

Pathways: Cell-Cell Junction Organization