CD57 anticorps
Aperçu rapide pour CD57 anticorps (ABIN5526903)
Antigène
Voir toutes CD57 (B3GAT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD57 Purified
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Specificité
- The mouse monoclonal antibody TB01 recognizes CD57, a carbohydrate extracellular antigen present mainly on NK cells, NK T cells, and in neural tissue.
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Réactivité croisée (Details)
- Human
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Purification
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
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Pureté
- > 95 % (by SDS-PAGE)
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Immunogène
- A pool of neuroblastoma cell lines
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Isotype
- IgM
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Indications d'application
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Flow cytometry: Recommended dilution: 1-4 μg/mL.
Immunohistochemistry: Recommended dilution: 5-10 μg/mL. -
Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
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Autre désignation
- CD57
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Sujet
- Beta-1,3-glucuronyltransferase 1,CD57, also known as HNK1 or Leu7, is a sulphated trisaccharide (3-O-sulfoglucuronic acid beta1-3 Gal beta1-4 GlcNAc) attached to several glycoproteins, including CD56, myelin glycoprotein PO, and neural cell adhesion molecule L1, as well as on glycolipids and chondroitin sulphate proteoglycans in the nervous system. It serves as a NK cell marker and it is expressed on well differentiated prostate cancers and uveal and cutaneous melanoma. CD57+ T cells are implicated as suppressors of T-cell responses.,HNK1, LEU7, 3-O-sulfoglucuronic acid beta1-3 Gal beta1-4 GlcNAc
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ID gène
- 27087
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UniProt
- Q9P2W7
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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