Cet anticorps anti-BNIP3 Polyclonal Lapin (ABIN5530561) détecte spécifiquement BNIP3 dans WB, IF et IHC (p).
L’anticorps est réactif avec des échantillons de Humain et Souris.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
BNIP3
(BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
Autre désignation
BNIP3
Sujet
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.