EIF3C anticorps (AA 538-566)

N° du produit ABIN5531093

Cet anticorps Lapin Polyclonal détecte spécifiquement EIF3C dans WB. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour EIF3C anticorps (AA 538-566) (ABIN5531093)

Antigène: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EIF3C anticorps

Épitope: AA 538-566

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EIF3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-566 amino acids from the Central region of human EIF3C.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur EIF3C

Antigène: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Autre désignation: EIF3C

Sujet: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Poids moléculaire: 105 kDa

ID gène: 8663

UniProt: Q99613

Pathways: Ribonucleoprotein Complex Subunit Organization