LIM Domain Binding 2 Protein anticorps (C-Term)

N° du produit ABIN5531520

L’anticorps Lapin Polyclonal anti-LIM Domain Binding 2 Protein a été validé pour WB et IHC (p). Il convient pour détecter LIM Domain Binding 2 Protein dans des échantillons de Humain.

Aperçu rapide pour LIM Domain Binding 2 Protein anticorps (C-Term) (ABIN5531520)

Antigène: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIM Domain Binding 2 Protein est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LIM Domain Binding 2 Protein anticorps

Épitope: AA 314-342, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LDB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human LDB2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LIM Domain Binding 2 Protein

Antigène: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Autre désignation: LDB2

Sujet: Genes encoding LIM domain-binding factors were initially isolated in a screen for proteins that physically interact with the LIM domains of nuclear proteins (summarized by Semina et al., 1998 [PubMed 9799849]). These proteins, such as the one encoded by the LDB2 gene, are capable of binding to a variety of transcription factors and are likely to function at enhancers to bring together diverse transcription factors and form higher order activation complexes or to block formation of such complexes (Jurata and Gill, 1997 [PubMed 9315627]). The family of genes encoding LIM domain-binding factors includes 2 members isolated from the mouse, Clim1 (Bach et al., 1997 [PubMed 9192866]) and Clim2/Lbd1/Nli (Agulnick et al., 1996 [PubMed 8918878], Jurata et al., 1996 [PubMed 8876198], Bach et al., 1997 [PubMed 9192866]) and their homologs cloned from the frog, chicken, and fly. The fact that LIM domain-binding factors are likely to be involved in the coordination of the transcriptional activity of many diverse factors might implicate them in human phenotypes characterized by multiple affected sites.

Poids moléculaire: 43 kDa

ID gène: 9079

UniProt: O43679

Pathways: Stem Cell Maintenance