MLF1 anticorps (N-Term)

N° du produit ABIN5531591

Détail du produit anti-MLF1 anticorps

Antigène: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Épitope: AA 35-62, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLF1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human MLF1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MLF1

Antigène: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Autre désignation: MLF1 (MLF1 Produits)

Synonymes: anticorps MLF1, anticorps HLS7, anticorps myeloid leukemia factor 1, anticorps myeloid leukemia factor 1 L homeolog, anticorps MLF1, anticorps mlf1.L, anticorps mlf1, anticorps Mlf1

Sujet: MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Poids moléculaire: 31 kDa

ID gène: 4291

UniProt: P58340