MTA1 anticorps (C-Term)

N° du produit ABIN5531615

Cet anticorps Lapin Polyclonal détecte spécifiquement MTA1 dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour MTA1 anticorps (C-Term) (ABIN5531615)

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MTA1 anticorps

Épitope: AA 659-687, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MTA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human MTA1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MTA1

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Autre désignation: MTA1

Sujet: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq].

Poids moléculaire: 81 kDa

ID gène: 9112

UniProt: Q13330

Pathways: Chromatin Binding