RBM5 anticorps (N-Term)

N° du produit ABIN5532044

Cet anticorps Lapin Polyclonal détecte spécifiquement RBM5 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour RBM5 anticorps (N-Term) (ABIN5532044)

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RBM5 anticorps

Épitope: AA 18-46, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RBM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human RBM5.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RBM5

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Autre désignation: RBM5

Sujet: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

Poids moléculaire: 92 kDa

ID gène: 10181

UniProt: P52756

Pathways: Ribonucleoprotein Complex Subunit Organization