ADRA2C anticorps (C-Term)

N° du produit ABIN5532816

L’anticorps anti-ADRA2C Polyclonal Lapin est utilisé pour la détection de ADRA2C dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour ADRA2C anticorps (C-Term) (ABIN5532816)

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ADRA2C anticorps

Épitope: AA 354-382, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ADRA2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 354-382 amino acids from the C-terminal region of human ADRA2C.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ADRA2C

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Autre désignation: ADRA2C

Sujet: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

Poids moléculaire: 50 kDa

ID gène: 152

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process