BTBD14A anticorps (C-Term)

N° du produit ABIN5532952

Cet anticorps anti-BTBD14A est un anticorps Lapin Polyclonal détectant BTBD14A dans WB. Adapté pour Humain.

Aperçu rapide pour BTBD14A anticorps (C-Term) (ABIN5532952)

Antigène: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTBD14A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BTBD14A anticorps

Épitope: AA 473-502, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NACC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the C-terminal region of human NACC2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BTBD14A

Antigène: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Autre désignation: NACC2

Sujet: BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

Poids moléculaire: 63 kDa

ID gène: 138151

UniProt: Q96BF6

Pathways: Positive Regulation of Response to DNA Damage Stimulus