BTBD14A anticorps (C-Term)
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- Antigène Voir toutes BTBD14A Anticorps
- BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))
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Épitope
- AA 473-502, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BTBD14A est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This NACC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the C-terminal region of human NACC2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product BTBD14A Anticorps primaire
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- Indications d'application
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))
- Autre désignation
- NACC2 (BTBD14A Produits)
- Synonymes
- anticorps NACC2, anticorps BTBD14A, anticorps BEND9, anticorps BTBD14, anticorps BTBD31, anticorps Btbd14a, anticorps 0610020I02Rik, anticorps AI448087, anticorps C030048H19Rik, anticorps NACC family member 2, anticorps nucleus accumbens-associated protein 2-like, anticorps nucleus accumbens associated 2, BEN and BTB (POZ) domain containing, anticorps NACC2, anticorps LOC100354269, anticorps Nacc2
- Sujet
- BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.
- Poids moléculaire
- 63 kDa
- ID gène
- 138151
- UniProt
- Q96BF6
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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