DHCR7 anticorps (C-Term)

N° du produit ABIN5533223

Cet anticorps Lapin Polyclonal détecte spécifiquement DHCR7 dans WB, IF et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour DHCR7 anticorps (C-Term) (ABIN5533223)

Antigène: DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHCR7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DHCR7 anticorps

Épitope: AA 437-463, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DHCR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-463 amino acids from the C-terminal region of human DHCR7.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IF starting dilution is: 1:25

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DHCR7

Antigène: DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))

Autre désignation: DHCR7

Sujet: This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS), a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.

Poids moléculaire: 54 kDa

ID gène: 1717

UniProt: Q9UBM7