RFXANK anticorps (AA 94-123)

N° du produit ABIN5533710

L’anticorps anti-RFXANK Polyclonal Lapin est utilisé pour la détection de RFXANK dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour RFXANK anticorps (AA 94-123) (ABIN5533710)

Antigène: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFXANK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RFXANK anticorps

Épitope: AA 94-123

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RFXANK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human RFXANK.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RFXANK

Antigène: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Autre désignation: RFXANK

Sujet: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.

Poids moléculaire: 28 kDa

ID gène: 8625

UniProt: O14593