ORC2 anticorps (AA 208-237)

N° du produit ABIN5534578

Cet anticorps anti-ORC2 est un anticorps Lapin Polyclonal détectant ORC2 dans WB. Adapté pour Humain.

Aperçu rapide pour ORC2 anticorps (AA 208-237) (ABIN5534578)

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ORC2 anticorps

Épitope: AA 208-237

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ORC2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human ORC2L.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ORC2

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Autre désignation: ORC2L

Sujet: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.

Poids moléculaire: 66 kDa

ID gène: 4999

UniProt: Q13416