L1CAM anticorps (C-Term)

N° du produit ABIN5535974

Détail du produit anti-L1CAM anticorps

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Épitope: AA 1154-1182, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This L1CAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1154-1182 amino acids from the C-terminal region of human L1CAM.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: L1CAM (L1CAM Produits)

Synonymes: anticorps l1cam-a, anticorps CAML1, anticorps CD171, anticorps HSAS, anticorps HSAS1, anticorps MASA, anticorps MIC5, anticorps N-CAM-L1, anticorps N-CAML1, anticorps NCAM-L1, anticorps S10, anticorps SPG1, anticorps L1, anticorps Hsas, anticorps Hyd, anticorps NCAML1, anticorps L1 cell adhesion molecule S homeolog, anticorps L1 cell adhesion molecule, anticorps l1cam.S, anticorps L1CAM, anticorps L1cam

Sujet: L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

Poids moléculaire: 140 kDa

ID gène: 3897

UniProt: P32004

Pathways: Synaptic Membrane