PITX2 anticorps (AA 122-151)

N° du produit ABIN5537325

L’anticorps anti-PITX2 Polyclonal Lapin est utilisé pour la détection de PITX2 dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour PITX2 anticorps (AA 122-151) (ABIN5537325)

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITX2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PITX2 anticorps

Épitope: AA 122-151

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids of human PITX2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IF starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PITX2

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Autre désignation: PITX2

Sujet: Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.

Poids moléculaire: 35 kDa

ID gène: 5308

UniProt: Q99697

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development