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SETD8 anticorps (AA 220-249)

SETD8 Reactivité: Humain WB, IHC (p), FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5537416
  • Antigène Voir toutes SETD8 Anticorps
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    Épitope
    • 22
    • 8
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 220-249
    Reactivité
    • 64
    • 22
    • 11
    Humain
    Hôte
    • 48
    • 16
    Lapin
    Clonalité
    • 47
    • 17
    Polyclonal
    Conjugué
    • 28
    • 8
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SETD8 est non-conjugé
    Application
    • 51
    • 36
    • 23
    • 9
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogène
    This SETD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human SETD8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SETD8 Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    Autre désignation
    SETD8 (SETD8 Produits)
    Synonymes
    anticorps KMT5A, anticorps PR-Set7, anticorps SET07, anticorps SET8, anticorps 2410195B05Rik, anticorps AA617402, anticorps AW536475, anticorps PR-SET7, anticorps setd8b, anticorps wu:fc23f12, anticorps zgc:171649, anticorps Pr-set7, anticorps RGD1305893, anticorps Setd8, anticorps kmt5a, anticorps kmt5a-a, anticorps setd8, anticorps setd8-a, anticorps set8a, anticorps setd8a, anticorps wu:fj33f02, anticorps zgc:153719, anticorps lysine methyltransferase 5A, anticorps lysine methyltransferase 5Ab, anticorps lysine methyltransferase 5A S homeolog, anticorps lysine methyltransferase 5Aa, anticorps KMT5A, anticorps Kmt5a, anticorps kmt5ab, anticorps kmt5a.S, anticorps kmt5aa
    Sujet
    SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. It is also involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.
    Poids moléculaire
    43 kDa
    ID gène
    387893
    UniProt
    Q9NQR1
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