PLK2 anticorps (C-Term)
Aperçu rapide pour PLK2 anticorps (C-Term) (ABIN5537875)
Antigène
Voir toutes PLK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 375-406, C-Term
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
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Immunogène
- This PLK2 (SNK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-406 amino acids from the C-terminal region of human PLK2 (SNK).
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Isotype
- Ig Fraction
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Indications d'application
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 2 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PLK2 (Polo-Like Kinase 2 (PLK2))
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Autre désignation
- PLK2
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Sujet
- Plks (polo-like kinases) encode serine/threonine kinases that are closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo-like kinases, which include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk (for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell proliferation. Plk protein accumulates in the cell during S and G2 phases of the cell cycle, and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
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Poids moléculaire
- 78 kDa
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ID gène
- 10769
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UniProt
- Q9NYY3
Antigène
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