IMPDH1 anticorps (N-Term)

N° du produit ABIN5538393

L’anticorps Lapin Polyclonal anti-IMPDH1 a été validé pour WB et IHC (p). Il convient pour détecter IMPDH1 dans des échantillons de Humain.

Aperçu rapide pour IMPDH1 anticorps (N-Term) (ABIN5538393)

Antigène: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IMPDH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IMPDH1 anticorps

Épitope: AA 84-113, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human IMPDH1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IMPDH1

Antigène: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Autre désignation: IMPDH1

Sujet: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 55 kDa

ID gène: 3614

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process