ACTC1 anticorps (N-Term)

N° du produit ABIN5539979

Cet anticorps Souris Monoclonal détecte spécifiquement ACTC1 dans WB, IHC (fro) et EIA. Il présente une réactivité envers Humain, Rat, Poisson zèbre (Danio rerio), Lapin et Porc.

Aperçu rapide pour ACTC1 anticorps (N-Term) (ABIN5539979)

Antigène: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Reactivité: Humain, Rat, Poisson zèbre (Danio rerio), Lapin, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACTC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: 22D3

Détail du produit anti-ACTC1 anticorps

Épitope: N-Term

Séquence: Ac-DDEETTALVC -COOH

Specificité: This 22D3 Monoclonal antibody is highly specific for Alpha-Cardiac Actin, and does not cross react with other Actin isoforms.

Purification: Purified

Immunogène: Peptide comprising the N-terminal nonapeptide of alpha-Cardiac Actin with an acetylated N-terminus coupled to keyhole limpet hemocyanin through the cysteine residue.

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Flow Cytometry. Immunoblotting. Immunofluorescence. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin-Embedded Sections. Recommended Dilutions : 1/100-1/1000 for Immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent and 1/1000-1/5000 for immunoblotting applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freeze-thaw cycles. Shelf life: One year from despatch.

Détails sur ACTC1

Antigène: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Autre désignation: alpha 1 cardiac muscle actin,actc1

Sujet: Among the six actin isoforms described in mammals, two are found in virtually all cells (β- and γ-cytoplasmic), two are detected in smooth muscle cells (α- and γ-smooth muscle) and two are present in striated muscles, one predominantly in skeletal (α-skeletal) and one in cardiac (α-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus, but the sequence of each of these actins is highly conserved in higher vertebrates. Cardiac α-actin, which is the main actin isoform in the adult heart, has also been shown to be the predominant form in early muscle development. In later development the expression of α-cardiac actin is down regulated and α-skeletal actin becomes the dominant isoform in the adult skeletal muscle.

Pathways: Myometrial Relaxation and Contraction