CX3CR1 anticorps

N° du produit ABIN5540227

Cet anticorps anti-CX3CR1 est un anticorps Souris Monoclonal détectant CX3CR1 dans IHC (p). Adapté pour Humain.

Aperçu rapide pour CX3CR1 anticorps (ABIN5540227)

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CX3CR1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1G4

Détail du produit anti-CX3CR1 anticorps

Specificité: This antibody detetcs CX3C Receptor 1. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein. The epitope has not been further characterized.

Purification: Affinity Chromatography on Protein G

Immunogène: DNA vaccine

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 2 μg/mL (1/100), pretreatment with proteinase K required. Suggested Positive Control: Human brain cortex.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL BSA

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CX3CR1

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Autre désignation: cx3cr1,gpr13

Sujet: G-protein coupled receptor 1 3 (GPR13) is a 355 amino acid protein that belongs to the G - protein coupled receptor 1 family. Biologically, the fractalkine (CX3CL1) to fractalkine receptor (CX3CR1) interactions play an important role in macrophage recruitment to target organs such as the brain, the intestine, the liver or the lungs. Accordingly, expression of the CX3CR1 has been described in inflammation - and tumor - associated macrophages, intestinal lamina propia macrophages, and B cells. Also, CX3CR1 mediates adhesive and migratory functions and acts as a coreceptor with CD4 for HIV - 1 virus gp160 envelope protein.

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin