GARS anticorps (AA 43-289)

N° du produit ABIN5540351

Cet anticorps Souris Monoclonal détecte spécifiquement GARS dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour GARS anticorps (AA 43-289) (ABIN5540351)

Antigène: GARS (Glycyl-tRNA Synthetase (GARS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GARS est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT4E10

Détail du produit anti-GARS anticorps

Épitope: AA 43-289

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human GARS (43-289aa) purified from E. coli.

Isotype: IgG1

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GARS

Antigène: GARS (Glycyl-tRNA Synthetase (GARS))

Autre désignation: glycyl-trna synthetase

Sujet: GARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetase that charge tRNAs with their cognate amino acids. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process