PTPRT anticorps (AA 1-742)
Aperçu rapide pour PTPRT anticorps (AA 1-742) (ABIN5540588)
Antigène
Voir toutes PTPRT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-742
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Specificité
- Monoclonal antibodies 3G4 and 3D7 have been directed against the extracellular domain of RPTPμ.
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Purification
- Purified
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Immunogène
- This antibody has been derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with ExG protein, secreted by NIH-3T3 transfected cells and purified with glutahione beads. The cells have been transfected using a fusion construct, termed ExG, encoding the entire ectodomain of the Human RPTPmu molecule (aa 1-742), fused COOH terminally to GST.
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Isotype
- IgG2a
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Indications d'application
- Western blot. Immunoprecipitation. Immunofluorescence. Flow Cytometry.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Buffer System: PBS Preservatives: 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Date de péremption
- 12 months
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- PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))
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Autre désignation
- ptprt
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Sujet
- Receptor-like protein tyrosine phosphatases (RPTPs) represent a new family of transmembrane proteins that are thought to transduce external signals by dephosphorylating phosphotyrosine residues on intracellular substrates. RPTPμ is a prototypic receptor-like protein-tyrosine phosphatase (RPTP) that mediates homotypic cell-cell interactions. Intracellularly, RPTPμ consists of a relatively large juxtamembrane region (about 150 amino acids) and two conserved phosphatase domains. As in most RPTPs, the first (membrane-proximal) PTP domain of RPTPμ is catalytically active, whereas its second (C-terminal) domain is inactive. RPTPμ is involved in cell-cell adhesion through homophilic interactions and may also play a key role in signal transduction and growth control.
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UniProt
- O14522
Antigène
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