SPTAN1 anticorps

N° du produit ABIN5540660

Cet anticorps Souris Monoclonal détecte spécifiquement SPTAN1 dans WB, ICC et IF. Il présente une réactivité envers Humain, Rat et Boeuf (Vache).

Aperçu rapide pour SPTAN1 anticorps (ABIN5540660)

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivité: Humain, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SPTAN1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 3D7

Détail du produit anti-SPTAN1 anticorps

Specificité: Specific for the ~240 k alpha II Spectrin protein.

Purification: Affinity Chromatography

Immunogène: Recombinant construct containing the seventh, eighth and ninth repeats of human alpha II spectrin expressed in and purified from E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/3000. Immunofluorescence: 1/500.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS Preservatives: 10 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SPTAN1

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Autre désignation: spectrin alpha chain (brain),sptan1

Sujet: The spectrin family of cytoskeletal proteins is comprised of 2 alpha genes (α1 and α2) and five beta genes (β1-β5). Spectrins have been shown to function as scaffolding proteins in mechanical support of the plasma membrane as well as bind other membrane proteins and lipids (Bennett and Baines 2001). Defects in spectrin genes have been linked to some forms of hereditary spherocytosis, a type of auto-hemolytic anemia which is characterized by spherical red blood cells that are more prone to lysis (Eber and Lux 2004).

UniProt: P07751

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization