HINT2 anticorps (AA 18-163)

N° du produit ABIN5540727

L’anticorps anti-HINT2 Monoclonal Souris est utilisé pour la détection de HINT2 dans des échantillons de Humain. Il a été validé pour WB, FACS et EIA.

Aperçu rapide pour HINT2 anticorps (AA 18-163) (ABIN5540727)

Antigène: HINT2 (Histidine Triad Nucleotide Binding Protein 2 (HINT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HINT2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: AT5B10

Détail du produit anti-HINT2 anticorps

Épitope: AA 18-163

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human HINT2 (18-163aa) purified from E. coli.

Isotype: IgG1

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur HINT2

Antigène: HINT2 (Histidine Triad Nucleotide Binding Protein 2 (HINT2))

Autre désignation: hint2

Sujet: Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent siglling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear.

UniProt: Q9BX68