MRGPRX2 anticorps

N° du produit ABIN5540874

L’anticorps Souris Monoclonal anti-MRGPRX2 a été validé pour IHC (p). Il convient pour détecter MRGPRX2 dans des échantillons de Humain.

Aperçu rapide pour MRGPRX2 anticorps (ABIN5540874)

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MRGPRX2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1D3

Détail du produit anti-MRGPRX2 anticorps

Specificité: This antibody detects Human MRGPRX2 (GPCRx11).

Purification: Protein G

Immunogène: DNA vaccine

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 1 μg/mL (1/200). Positive control: Human placenta.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur MRGPRX2

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Autre désignation: mrgprx2

Sujet: MRGPRX2 or cortistatin receptor is a 330 amino acid protein that belongs to the G - protein coupled receptor 1 family. Mas - related G - protein - coupled receptors (Mrgprs) represent a large family of orphan receptors specifically expressed in small - diameter nociceptive primary sensory neurons. Physiological functions include mediation of itch or regulat ion of persistent pathological pain. Cortistatin - 14, which is involved in sleep regulation, locomotor activity, and cortical function, seems to be a high potency ligand at this receptor. Also, the multifunctional antibacterial protein LL - 37 has been shown to activate cells presumably through MRGPRX2.

UniProt: Q96LB1