ASF1B anticorps (AA 1-202)

N° du produit ABIN5541030

L’anticorps Souris Monoclonal anti-ASF1B a été validé pour WB et EIA. Il convient pour détecter ASF1B dans des échantillons de Humain.

Aperçu rapide pour ASF1B anticorps (AA 1-202) (ABIN5541030)

Antigène: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ASF1B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT1D4

Détail du produit anti-ASF1B anticorps

Épitope: AA 1-202

Specificité: Recognizes Human ASF1B. Other species not tested.

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human ASF1B (1-202aa) purified from E. coli.

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ASF1B

Antigène: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Autre désignation: asf1b

Sujet: ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative stress.

UniProt: Q9NVP2

Pathways: Regulation of Cell Size