ICOSLG anticorps (Extracellular Domain)

N° du produit ABIN5541150

L’anticorps anti-ICOSLG Monoclonal produit chez le Souris a été validé pour FACS et EIA. Il convient pour la détection de ICOSLG dans des échantillons provenant de Humain. }

Aperçu rapide pour ICOSLG anticorps (Extracellular Domain) (ABIN5541150)

Antigène: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ICOSLG est non-conjugé

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: GM13C1

Détail du produit anti-ICOSLG anticorps

Épitope: Extracellular Domain

Specificité: This antibody recognizes Human CD275 / ICOS Ligand. Other species not tested.

Purification: Affinity Chromatography on Protein G

Immunogène: Genetic immunisation with cDNA encoding Human ICOSL (Extracellular Domain).

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 1.2 μg/10 6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ICOSLG

Antigène: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Autre désignation: cd275,icos ligand

Sujet: Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS)(1). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secre-tion (2,3).

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation