CEACAM5 anticorps

N° du produit ABIN5541179

Cet anticorps Souris Monoclonal détecte spécifiquement CEACAM5 dans FACS, IF, WB, IHC (fro), EIA et ICC. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour CEACAM5 anticorps (ABIN5541179)

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM5 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC)

Clone: 26-3-13

Détail du produit anti-CEACAM5 anticorps

Specificité: This antibody recognizes exclusively CECAM5.

Purification: Protein G Chromatography

Immunogène: Extracted protein of CEACAM5. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Flow Cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1/200. Western blot: 4 μg/mL. Immunohistochemistry on Cryo -Sections: 1-2 μg/10

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2 without preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-CEACAM5 (ABIN5541179)

Schmitter, Agerer, Peterson, Munzner, Hauck: "Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens." dans: The Journal of experimental medicine, Vol. 199, Issue 1, pp. 35-46, (2004) (PubMed).

Détails sur CEACAM5

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Autre désignation: cd66e,ceacam5

Sujet: CEACAM5 (CEA-related cell adhesion molecule 5, CEA) belongs to the carcinoembryonic antigen (CEA) gene family (1,2). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 180,000-200,000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cell of the tongue, esophagus and cervix. CEACAM5 is used as a tumor marker for early detection of recurrent disease due to its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas (3). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).

UniProt: P06731