CEACAM5 anticorps
Aperçu rapide pour CEACAM5 anticorps (ABIN5541181)
Antigène
Voir toutes CEACAM5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts to CD66e / CEACAM5. Species: Human.
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Purification
- Affinity Chromatography on Protein G
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Immunogène
- Immunisation with extracted protein of CEACAM5
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Isotype
- IgG2a
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Indications d'application
- Flow Cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Western blot: 4 μg/mL. Immunohistochemistry on Frozen Sections: 1-2 μg/10 cells (on cryosections).
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate buffered saline, pH 7.2
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Date de péremption
- 12 months
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- CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
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Autre désignation
- cd66e,ceacam5
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Sujet
- CEACAM5 (CEA-related cell adhesion molecule 5, CEA) belongs to the carcinoembryonic antigen (CEA) gene family (1,2). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 180,000-200,000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cell of the tongue, esophagus and cervix. CEACAM5 is used as a tumor marker for early detection of recurrent disease due to its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas (3). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).
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UniProt
- P06731
Antigène
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