FUBP1 anticorps (AA 279-448)

N° du produit ABIN5541255

L’anticorps anti-FUBP1 Monoclonal Souris est utilisé pour la détection de FUBP1 dans des échantillons de Humain. Il a été validé pour WB, IF, ICC et EIA.

Aperçu rapide pour FUBP1 anticorps (AA 279-448) (ABIN5541255)

Antigène: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FUBP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

Clone: AT14F5

Détail du produit anti-FUBP1 anticorps

Épitope: AA 279-448

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human FUBP1 (279-448aa) purified from E.coli.

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur FUBP1

Antigène: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Autre désignation: fubp1

Sujet: FUBP1 is a transcriptiol regulator and fulfills an important function in the precise control of c-myc transcription. The c-Myc protein is a transcription factor which regulates the transcription of many different target genes that play a role in proliferation, cell cycle progression, differentiation, apoptosis and cell metabolism. Consequently, FUBP1 is also involved in the regulation of proliferation and differentiation, as confirmed by different experimental approaches. Knockdown of FUBP1 or expression of a domint-negative FUBP1 (D-binding domain lacking effector activity) led to proliferation arrest in U2OS and Saos-2 osteosarcoma cells due to reduced c-myc expression.

UniProt: Q96AE4